I recommend you to watch this video to get you started with TSplus : https://terminalserviceplus.com/videos/start-your-remote-desktop-solution.php
You will find here a documentation on how to publish new applications : https://terminalserviceplus.com/docs/application-publishing
And how to assign these applications to users : https://terminalserviceplus.com/docs/assigning-applications-to-users-or-groups